Apollo 1 - January 27, 1967
Astronauts Grissom, White and Chaffee perish in a launch pad fire during a routine countdown rehearsal.

STS 51-L - January 28, 1986
The seven-member crew of space shuttle Challenger is lost 73 seconds after launch.

STS-107 - February 1, 2003
The space shuttle Columbia and its seven astronauts are lost during reentry over Texas.